SUMMARY The COVID-19 pandemic is an unprecedented global challenge. Highly variable in its presentation, spread and clinical outcome, novel point-of-care diagnostic classifiers are urgently required. Here, we describe a set of COVID-19 clinical classifiers discovered using a newly designed low-cost high throughput mass spectrometry-based platform. Introducing a new sample preparation pipeline coupled with short-gradient high-flowSigue leyendo «Clinical classifiers of COVID-19 infection from novel ultra-high-throughput proteomics»
Archivo de etiqueta: SWATH
SWATH-MS®
SWATH-MS® (Sequential Window Acquisition of All Theoretical Fragment Ion Mass Spectra) Es un método de adquisición que genera mapas de proteínas globales y cuantitativas utilizando la combinación de la adquisición de datos independientes (DIA) y el análisis de datos específicos, de esta forma, aumenta enormemente el rendimiento de identificación/cuantificación de péptidos en comparación con elSigue leyendo «SWATH-MS®»
Comparing SRM and SWATH Methods for Quantitation of Bovine Muscle Proteomes
ABSTRACT Mass spectrometry (MS) has become essential for efficient and accurate quantification of proteins and proteomes and, thus, a key technology throughout all biosciences. However, validated MS methods are still scarce for meat quality research applications. The objective of this work was to develop and compare two targeted proteomic methods, namely, selected reaction monitoring (SRM)Sigue leyendo «Comparing SRM and SWATH Methods for Quantitation of Bovine Muscle Proteomes»
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